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Tiagabine hydrochloride
Item number: TGM-T7000-100mg
Description: Tiagabine hydrochloride (NO050328 hydrochloride) is the hydrochloride salt form of tiagabine, a nipecotic acid derivative with anticonvulsant property. A selective gamma-aminobutyric acid (GABA) reuptake inhibitor. Target: GABA Receptor. Smiles: Cl.Cc1ccsc1\C(=C\CCN1CCC[C@H](C1)C(O)=O)c1sccc1C....
| Keywords: | TGB hydrochloride, NO050328 hydrochloride, Gabitril, Gabitril hydrochloride, NO328 hydrochloride |
| Application: | Targets solute carrier family 6 (neurotransmitter transporter, GABA) member 1 (SLC6A1, GAT1) |
| CAS | 145821-59-6 |
| MW: | 412.01 D |
From 46.00€
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Tiagabine (hydrochloride)
Item number: Cay22926-10
Tiagabine is an inhibitor of GABA transporter 1 (GAT-1, IC50 = 49 nM for GAT-1 expressed in CHO cells). It inhibits seizures induced by DMCM in mice (ED50 = 1.2 mg/kg, i.p.). Tiagabine reduces allodynia in a rodent model of neuropathic pain when used at a dose of 72.8 µmol/kg, and it acts synergistically with...
| Keywords: | ABT-569, (3R)-1-[4,4-bis(3-methyl-2-thienyl)-3-buten-1-yl]-3-piperidinecarboxylic acid, monohydrochloride |
| Application: | GABA mimetic antiepileptic |
| CAS | 145821-59-6 |
| MW: | 412 D |
From 44.00€
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