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NNC-711 (hydrochloride)
Item number: Cay29687-1
NNC-711 is an inhibitor of GABA transporter 1 (GAT-1, IC50 = 0.04 µM for the human transporter). It is selective for GAT-1 over human GAT-3 and BGT-3 (IC50s = 1,700 and 622 µM, respectively), rat GAT-2 (IC50 = 171 µM), and a panel of 21 receptors and ion channels (IC50s = >50 µM for all) in radioligand binding...
| Keywords: | NNC 05-711, NO-711, 1-[2-[[(diphenylmethylene)amino]oxy]ethyl]-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid,... |
| Application: | GAT-1 inhibitor |
| CAS | 145645-62-1 |
| MW: | 386.9 D |
From 49.00€
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NNC 05-711
Item number: TGM-T23075-1mg
Description: NNC 05-711 (NO-711 hydrochloride) is a potent and selective inhibitor of GAT-1 (GABA transporter 1), which inhibits GABA reuptake and thereby increases GABA levels in the synaptic gap, exerting anticonvulsant and analgesic effects. Target: GABA Receptor. Smiles: Cl.OC(=O)C1=CCCN(CCON=C(c2ccccc2)c2ccccc2)C1
| Keywords: | NNC05-711 , NNC 05711 , NO-711 hydrochloride |
| Application: | GAT-1 inhibitor |
| CAS | 145645-62-1 |
| MW: | 386.87 D |
From 40.00€
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