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SR-3029
SR-3029

Item number: TGM-T3972-10mg

Description: SR-3029 is a highly potent and specific inhibitor of CK1delta/CK1epsilon. Target: Casein Kinase. Smiles: Fc1cccc(c1)-n1cnc2c(NCc3nc4ccc(F)c(F)c4[nH]3)nc(nc12)N1CCOCC1. References: Rosenberg LH,et al. Therapeutic targeting of casein kinase 1delta in breast cancer. Sci Transl Med. 2015 Dec...
Keywords: SR3029
Application: Casein kinase 1 delta / epsilon inhibitor
CAS 1454585-06-8
MW: 480.45 D
From 31.00€ *
Review
SR 3029
SR 3029

Item number: Cay27048-5

SR 3029 is an inhibitor of casein kinase 1delta (CK1delta) and CK1epsilon (IC50s = 44 and 260 nM, respectively). It is selective for CK1delta and CK1epsilon over 438 kinases in a panel but also inhibits MYLK4, FLT3, Cdk4/cyclin D1, and MARK2 by greater than 90% at 10 µM. SR 3029 inhibits Cdk4/cyclin D1, Cdk4/cyclin...
Keywords: N-[(6,7-difluoro-1H-benzimidazol-2-yl)methyl]-9-(3-fluorophenyl)-2-(4-morpholinyl)-9H-purin-6-amine
Application: Casein kinase 1 delta / epsilon inhibitor
CAS 1454585-06-8
MW: 480.5 D
From 117.00€ *
Review