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Item number: TGM-T15781-100mg

Description: LP-935509 is highly brain-penetrant and reverses fully established pain behavior following the SNL procedure. LP-935509 is an effective inhibitor of BIKE (IC50=14 nM) and a modest inhibitor of cyclin G-associated kinase(GAK, IC50=320 nM). LP-935509 is also a ATP-competitive inhibitor of adapter...

Application:	AAK1 / BIKe inhibitor
CAS	1454555-29-3
MW:	396.44 D

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LP-935509

Item number: Cay37283-1

LP-935509 is an inhibitor of AP2-associated protein kinase 1 (AAK1) and BMP2-inducible kinase (BIKe, IC50s = 3.3 and 14 nM, respectively). It is selective for AAK1 and BIKe over µ- and kappa-opioid, as well as alpha2A- and alpha2C-adrenergic, receptors (IC50s = >30 µM for all), alpha1 and alpha2 subunit-containing...

Keywords:	4-[3-(2-methoxy-3-pyridinyl)pyrazolo[1,5-a]pyrimidin-5-yl]-1-piperazinecarboxylic acid, 1-methylethyl ester
Application:	AAK1 / BIKe inhibitor
CAS	1454555-29-3
MW:	396.4 D

From 55.00€ *

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