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6,7-dihydroxy Bergamottin
6,7-dihydroxy Bergamottin

Item number: Cay10009598-1

6,7-dihydroxy Bergamottin (6,7-DHB) is a potent inhibitor of CYP3A4 (IC50 = 25 µM). It appears to be the primary compound in grapefruit juice that is responsible for inhibition of testosterone 6beta-hydrolase activity. Ingestion of grapefruit juice during treatment regimes with drugs normally metabolized by...
Keywords: 6,7-DHB, 4-[[(2E)-6,7-dihydroxy-3,7-dimethyl-2-octenyl]oxy]-7H-fuoro[3,2-g][1]benzopyran-7-one
Application: CYP3A4 inhibitor
CAS 145414-76-2
MW: 372.4 D
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