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Bisindolylmaleimide XI (hydrochloride)
Bisindolylmaleimide XI (hydrochloride)

Item number: Cay11073-1

Bisindolylmaleimide XI (BIM XI) is a selective, cell-permeable protein kinase C (PKC) inhibitor that displays 10-fold greater selectivity for PKCalpha (IC50 = 9 nM) and 4-fold greater selectivity for PKCbetaI (IC50 = 28 nM) over Ca2+-independent PKCepsilon (IC50 = 108 nM). Inhibition of PKCalpha by BIM XI and other...
Keywords: BIM XI, Ro 31-0432,...
Application: PKC inhibitor
CAS 145333-02-4
MW: 489 D
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