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AG-112
Item number: Cay45208-10
An EGFR inhibitor, inhibits EGFR-catalyzed phosphorylation of poly(GAT) in a cell-free assay (IC50 = 0.125 µM), inhibits calcineurin phosphatase activity in a cell-free assay (IC50 = 30 µM), inhibits diabetes-induced growth of VSMCs isolated from type 2 diabetic rats, reduces diabetes-induced increases in superoxide...
| Keywords: | 2-amino-3-[(4-hydroxyphenyl)methylene]-1-propene-1,1,3-tricarbonitrile |
| Application: | EGFR inhibitor |
| CAS | 144978-82-5 |
| MW: | 236.23 D |
From 70.00€
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Tyrphostin AG 112
Item number: TGM-T8534-100mg
Description: Tyrphostin AG 112 is an inhibitor of EGFR phosphorylation. Target: EGFR. Smiles: C(=C(C(=C(C#N)C#N)N)C#N)C1=CC=C(O)C=C1. References: Rodrigo Franco, et al. Epidermal Growth Factor Receptor Is Activated by Hyposmolarity and Is an Early Signal Modulating Osmolyte Efflux Pathways in Swiss 3T3 Fibroblasts....
| CAS | 144978-82-5 |
| MW: | 236.23 D |
From 38.00€
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