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Item number: TGM-T5044-100mg

Description: Futibatinib (FGFR-IN-1) is a novel, potent and highly selective FGFR inhibitor, used for antitumor treatment. Target: FGFR. Smiles: COc1cc(OC)cc(c1)C#Cc1nn([C@H]2CCN(C2)C(=O)C=C)c2ncnc(N)c12. References: Hiroaki OCHIIWA, et al. Antitumor drug for intermittent administration of fgfr inhibitor. WO...

Keywords:	TAS120, FGFR-IN-1
Application:	Targets fibroblast growth factor receptor 2 [EC:2.7.10.1] (FGFR2, CD332)
CAS	1448169-71-8
MW:	418.45 D

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TAS 120

Item number: Cay21136-1

TAS 120 is an orally bioavailable inhibitor of fibroblast growth factor receptors (FGFRs) that irreversibly inhibits all four FGFR subtypes at nanomolar concentrations. It prevents phosphorylation of FGFRs and impedes downstream signaling pathways in cells. TAS 120 blocks the proliferation of human cancer cell lines...

Keywords:	1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-pyrrolidinyl]-2-propen-1-one
Application:	FGFR inhibitor
CAS	1448169-71-8
MW:	418.5 D

From 78.00€ *

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