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Futibatinib
Item number: BPS-83938-1
Futibatinib, also known as TAS-120 is an orally bioavailable, highly selective, and irreversible FGFR1-4 inhibitor, currently being used in the treatment of intrahepatic cholangiocarcinoma, a bile duct cancer in the liver. Fibroblast growth factor 21 (FGF-21) is a member of the FGF family that lacks the...
| Application: | Cell based assays |
| CAS | 1448169-71-8 |
| MW: | 418.25 D |
From 292.00€
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TAS 120
Item number: Cay21136-1
TAS 120 is an orally bioavailable inhibitor of fibroblast growth factor receptors (FGFRs) that irreversibly inhibits all four FGFR subtypes at nanomolar concentrations. It prevents phosphorylation of FGFRs and impedes downstream signaling pathways in cells. TAS 120 blocks the proliferation of human cancer cell lines...
| Keywords: | 1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-pyrrolidinyl]-2-propen-1-one |
| Application: | FGFR inhibitor |
| CAS | 1448169-71-8 |
| MW: | 418.5 D |
From 85.00€
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Futibatinib
Item number: TGM-T5044-100mg
Description: Futibatinib (FGFR-IN-1) is a novel, potent and highly selective FGFR inhibitor, used for antitumor treatment. Target: FGFR. Smiles: COc1cc(OC)cc(c1)C#Cc1nn([C@H]2CCN(C2)C(=O)C=C)c2ncnc(N)c12. References: Hiroaki OCHIIWA, et al. Antitumor drug for intermittent administration of fgfr inhibitor. WO...
| Keywords: | TAS120, FGFR-IN-1 |
| Application: | Targets fibroblast growth factor receptor 2 [EC:2.7.10.1] (FGFR2, CD332) |
| CAS | 1448169-71-8 |
| MW: | 418.45 D |
From 46.00€
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