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2-D08
Item number: Cay20459-5
2-D08 is a synthetic flavone that inhibits sumoylation. It completely inhibits sumoylation in microfluidic electrophoretic mobility shift and kinetic assays at a concentration of 30 µM. 2-D08 inhibits sumoylation of topoisomerase I in the breast cancer cell lines ZR-75-1 and BT-474. It specifically disrupts the...
| Keywords: | 2-(2,3,4-trihydroxyphenyl)-4H-1-benzopyran-4-one |
| Application: | Cell-permeable, potent sumoylation inhibitor |
| CAS | 144707-18-6 |
| MW: | 270.2 D |
From 49.00€
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2-D08
Item number: TGM-T7379-100mg
Description: 2-D08 is a synthetic flavone that inhibits sumoylation, also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect. Target: E1/E2/E3 Enzyme, TAM Receptor. Smiles: Oc1ccc(c(O)c1O)-c1cc(=O)c2ccccc2o1. References: Kim Y , Nagy K , Keyser S , et al. An...
| Application: | Cell-permeable, potent sumoylation inhibitor |
| CAS | 144707-18-6 |
| MW: | 270.24 D |
From 49.00€
*
