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ABX-1431
Item number: TGM-T5353-100mg
Description: ABX-1431 (Elcubragistat) is a selective and orally available CNS-penetrant monoacylglycerol lipase (MAGL/MGLL) inhibitor (IC50: 14 nM). Target: Lipase. Smiles: FC(F)(F)C(OC(=O)N1CCN(Cc2ccc(cc2N2CCCC2)C(F)(F)F)CC1)C(F)(F)F. References: Cisar JS, et al. Identification of ABX-1431, a Selective Inhibitor of...
| Keywords: | Elcubragistat |
| Application: | MAGL inhibitor |
| CAS | 1446817-84-0 |
| MW: | 507.39 D |
From 31.00€
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ABX-1431
Item number: Cay26023-1
ABX-1431 is an inhibitor of monoacylglycerol lipase (MAGL, IC50s = 14 and 27 nM for human and rat enzyme, respectively). It is selective for MAGL over ABHD6 and PLA2G7 (IC50s = 2.7 and >10 µM, respectively), as well as a panel of 33 serine hydrolases and a panel of 95 enzymes, receptors, transporters, and ion...
| Keywords: | 4-[[2-(1-pyrrolidinyl)-4-(trifluoromethyl)phenyl]methyl]-1-piperazinecarboxylic acid,... |
| Application: | MAGL inhibitor |
| CAS | 1446817-84-0 |
| MW: | 507.4 D |
From 67.00€
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