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NSC 668036
Item number: Cay23499-1
NSC 668036 is an inhibitor of the Dishevelled (Dvl) protein PDZ domain (Kd = 240 µM for mouse Dvl1 PDZ domain). NSC 668036 interacts with Dvl PDZ at the same binding site as Dapper and Frizzled, native binding partners in the Wnt signaling pathway. NSC 668036 (180 ng) reduces expression of the Wnt target gene,...
| Keywords: | N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-alanine, (1S)-1-carboxy-2-methylpropyl ester |
| Application: | Dishevelled PDZ domain inhibitor |
| CAS | 144678-63-7 |
| MW: | 460.5 D |
From 56.00€
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NSC-668036
Item number: TGM-T28211-10mg
Description: NSC-668036 is an inhibitor of Dishevelled (Dvl) protein, a key protein in wnt signaling. Target: Others. Smiles: C(C(NC(C(OC(C(C)C)C(O)=O)=O)C)=O)(OC(C(NC(OC(C)(C)C)=O)C)=O)C(C)C. References: Wang C, Dai J, Sun Z, Shi C, Cao H, Chen X, Gu S, Li Z, Qian W, Han X. Targeted inhibition of disheveled PDZ...
| Application: | Dishevelled PDZ domain inhibitor |
| CAS | 144678-63-7 |
| MW: | 460.52 D |
From 125.00€
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