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Item number: Cay28733-10

GR113808 is an antagonist of the serotonin (5-HT) receptor subtype 5-HT4. It binds to 5-HT4 receptors with an IC50 value of 0.4 nM in COS-7 cells expressing the human recombinant receptor and in guinea pig striatal membranes (IC50 = 0.5 nM). GR113808 is selective for 5-HT4 receptors over 5-HT1 receptors (Kis = >10...

Keywords:	1-methyl-1H-indole-3-carboxylic acid, [1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]methyl ester
Application:	Serotonin (5-HT) receptor subtype 5-HT4 antagonist
CAS	144625-51-4
MW:	393.5 D

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