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Belvarafenib
Item number: Cay31460-1
Belvarafenib is an inhibitor of B-RAF and C-RAF (IC50s = 41, 7, and 2 nM for wild-type B-RAF, B-RAFV600E, and wild-type C-RAF, respectively). It is cytotoxic to B-RAFV600E-expressing A375 and SK-MEL-28 melanoma cells (IC50s = 57 and 69 nM, respectively), as well as COLO 205 and HCT116 colon and B-CPAP and CAL-62...
| Keywords: | GDC-5573, HM95573,... |
| Application: | B-RAF / C-RAF inhibitor |
| CAS | 1446113-23-0 |
| MW: | 478.9 D |
From 69.00€
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Belvarafenib
Item number: TGM-T5634-100mg
Description: Belvarafenib is a potent and pan RAF inhibitor with antineoplastic activity. The IC50 values of Belvarafenib are 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively. Target: Raf. Smiles: Cc1ccc2c(Nc3cccc(Cl)c3F)nccc2c1NC(=O)c1csc2c(N)ncnc12. References: Son J B , Jung S H , Choi Ii W , et...
| Application: | B-RAF / C-RAF inhibitor |
| CAS | 1446113-23-0 |
| MW: | 478.93 D |
From 93.00€
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