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Item number: Cay31460-1

Belvarafenib is an inhibitor of B-RAF and C-RAF (IC50s = 41, 7, and 2 nM for wild-type B-RAF, B-RAFV600E, and wild-type C-RAF, respectively). It is cytotoxic to B-RAFV600E-expressing A375 and SK-MEL-28 melanoma cells (IC50s = 57 and 69 nM, respectively), as well as COLO 205 and HCT116 colon and B-CPAP and CAL-62...

Keywords:	GDC-5573, HM95573,...
Application:	B-RAF / C-RAF inhibitor
CAS	1446113-23-0
MW:	478.9 D

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