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Leelamine
Item number: Cay10006148-5
Leelamine is a diterpene amine that has been found in gum resin and has diverse biological activities. It inhibits pyruvate dehydrogenase kinase (PDHK, IC50 = 9.5 µM). Leelamine is active against the plant pathogenic fungus B. cinerea (EC50 = 70 µM). It induces apoptosis in UACC-903 and 1205Lu melanoma cell lines...
| Keywords: | Dehydroabietylamine, 1R,2,3,4,4aS,9,10,10aR-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine |
| Application: | PDK inhibitor |
| CAS | 1446-61-3 |
| MW: | 285.5 D |
From 58.00€
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Dehydroabiethylamine
Item number: TGM-T19783-1g
Description: Dehydroabiethylamine (NSC-2955) is an inducer of hepatic CYP2B activity. Dehydroabiethylamine inhibits pyruvate dehydrogenase kinases (PDKs) and intracellular cholesterol transport with anti-tumor activity. Target: PDK, P450. Smiles: [H][C@@]12CCc3cc(ccc3[C@@]1(C)CCC[C@@]2(C)CN)C(C)C. References: Kuzu...
| Keywords: | Leelamine, Dehydroabietylamine, NSC-2955, NSC 2955, Leelamine free base, NSC2955 |
| Application: | PDK inhibitor |
| CAS | 1446-61-3 |
| MW: | 285.47 D |
From 29.00€
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