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Item number: Cay43485-10

GPR84 antagonist 8 is an antagonist of G protein-coupled receptor 84 (GPR84). It inhibits calcium mobilization induced by 6-OAU (Cay17687) in HEK293 cells expressing human GPR84 and Galpha16 (IC50 = 716 nM). GPR84 antagonist 8 (10 µM) inhibits 6-OAU-enhanced phagocytosis of E. coli by primary mouse bone...

Keywords:	EN 818470, G Protein-coupled Receptor 84 Antagonist 8,...
Application:	GPR84 antagonist
CAS	1445846-30-9
MW:	421.45 D

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GPR84 antagonist 8

Item number: TGM-T11462-100mg

Description: GPR84 antagonist 8 is a selective GPR84 antagonist. Target: GPR. Smiles: O=c1nc(OCC2COCCO2)cc2-c3ccc(OCc4ccccn4)cc3CCn12. References: Recio C, et al. Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages. Front Immunol. 2018 Jun 20,9:1419.

CAS	1445846-30-9
MW:	421.45 D

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