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TFMB-(R)-2-HG
TFMB-(R)-2-HG

Item number: TGM-T17065-100mg

Description: TFMB-(R)-2-HG is a cell membrane-permeable (R)-2-HG, an oncogenic factor in acute myeloid leukemia. It impairs SCF ER-Hoxb8 cell differentiation in response to estrogen withdrawal. Target: Others. Smiles: FC(F)(F)c1cccc(COC(=O)[C@H]2CCC(=O)O2)c1. References: Losman JA, et al. (R)-2-hydroxyglutarate is...
Application: Cell-permeable leukemogenesis promoter
CAS 1445700-01-5
MW: 288.22 D
From 71.00€ *
Review
TFMB-R-2-HG
TFMB-R-2-HG

Item number: Cay20461-1

TFMB-R-2-HG is a cell-permeable form of (R)-2-hydroxyglutarate ((R)-2-HG). (R)-2-HG is structurally similar to alpha-ketoglutarate and competitively inhibits alpha-ketoglutarate-dependent dioxygenases, including lysine demethylases and DNA hydroxylases. TFMB-R-2-HG has been used to assess the role of (R)-2-HG in...
Keywords: (2R)-tetrahydro-5-oxo-2-furancarboxylic acid, [3-(trifluoromethyl)phenyl]methyl ester
Application: Cell-permeable leukemogenesis promoter
CAS 1445700-01-5
MW: 288.2 D
From 85.00€ *
Review