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BAY-1161909
Item number: Cay41108-1
BAY-1161909 is an inhibitor of monopolar spindle 1 (Mps1, IC50 = 0.34 nM). It inhibits metaphase arrest induced by the antimitotic agent nocodazole (Cay-13857) in HeLa cells (IC50 = 56 nM). BAY-1161909 inhibits proliferation in a panel of 86 cancer cell lines (median IC50 = 6.7 nM). In vivo, BAY-1161909 (2.5 mg/kg)...
| Keywords: | Empesertib,... |
| Application: | Mps1 (multipolar spindle 1) inhibitor |
| CAS | 1443763-60-7 |
| MW: | 559.6 D |
From 84.00€
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Empesertib
Item number: TGM-T8487-100mg
Description: Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity. Target: Kinesin. Smiles: COc1cc(ccc1Nc1nc2ccc(cn2n1)-c1ccc(NC(=O)[C@H](C)c2ccc(F)cc2)cc1)S(C)(=O)=O. References: SCHULZE, Volker, et al. PRODRUG DERIVATIVE SOF...
| Keywords: | BAY 1161909 |
| Application: | Mps1 (multipolar spindle 1) inhibitor |
| CAS | 1443763-60-7 |
| MW: | 559.61 D |
From 78.00€
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