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CCG-203971

Item number: TGM-T4306-100mg

Description: CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 µM), with 87% inhibition of SRE activation achieved at 100 µM. This compound also inhibits PC-3 cell migration (IC50: 4.2 µM), as determined by a scratch wound assay. CCG-203971(CCG203971) causes no...

Keywords:	CCG203971
Application:	SRE activation inhibitor
CAS	1443437-74-8
MW:	408.88 D

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CCG-203971

Item number: Cay15075-5

Signaling through small G proteins of the RhoA subfamily, including RhoC, induces actin-regulated cytosolic-to-nuclear translocation of the oncogene product megakaryoblastic leukemia 1 (MKL1), which binds to serum response factor (SRF). The MKL1/SRF complex, in turn, activates the transcription of serum response...

Keywords:	N-(4-chlorophenyl)-1-[3-(2-furanyl)benzoyl]-3-piperidinecarboxamide
Application:	SRE activation inhibitor
CAS	1443437-74-8
MW:	408.9 D

From 66.00€ *

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