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YYA-021
YYA-021

Item number: Cay22915-1

YYA-021 is a small molecule CD4 mimetic that competitively inhibits gp120 from interacting with CD4, preventing HIV entry into cells. It inhibits infection of PM1/CCR5 cells from lab isolates of the HIV-1 strains IIIB (X4, Sub B) and 89.6 (dual, Sub B) (IC50s = 23 and 41 µM, respectively) as well as clinical...
Keywords: N1-(4-methylphenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)-ethanediamide
Application: CD4 mimetic
CAS 144217-65-2
MW: 317.4 D
From 49.00€ *
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YYA-021
YYA-021

Item number: TGM-T6256-100mg

Description: YYA-021 inhibits HIV entry, with high anti-HIV activity and low cytotoxicity. Target: HIV Protease, gp120/CD4. Smiles: Cc1ccc(NC(=O)C(=O)NC2CC(C)(C)NC(C)(C)C2)cc1. References: Otsuki H, et al. J Gen Virol. 2013, 94(Pt 12), 2710-2716.
Keywords: YYA 021
Application: CD4 mimetic
CAS 144217-65-2
MW: 317.43 D
From 29.00€ *
Review