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Item number: Cay29170-1

Piclamilast is a phosphodiesterase 4 (PDE4) inhibitor (IC50 = 0.31 nM). It is selective for PDE4 over PDE1, PDE2, PDE3, PDE5, and PDE7A in cell-free assays (IC50s = >100, 40, >100, 14, and >10 µM, respectively). Piclamilast inhibits superoxide production by guinea pig eosinophils and histamine-induced contraction in...

Keywords:	RP 73401, RPR 73401, 3-(cyclopentyloxy)-N-(3,5-dichloro-4-pyridinyl)-4-methoxy-benzamide
Application:	PDE4 inhibitor
CAS	144035-83-6
MW:	381.3 D

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Piclamilast

Item number: TGM-T23154-100mg

Description: Piclamilast (RP 73401) is a PDE4 inhibitor. Target: PDE. Smiles: COc1ccc(cc1OC1CCCC1)C(=O)Nc1c(Cl)cncc1Cl. References: Manuel Mata, et al. Piclamilast inhibits the pro-apoptotic and anti-proliferative responses of A549 cells exposed to H(2)O(2) via mechanisms involving AP-1 activation. Free Radic Res....

Keywords:	RP 73401, RPR 73401
CAS	144035-83-6
MW:	381.25 D

From 42.00€ *

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