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SB-200646 (hydrochloride)
Item number: Cay30973-1
SB-200646 is a dual antagonist of the serotonin (5-HT) receptor subtypes 5-HT2C (Ki = 125 nM in isolated rat cortex) and 5-HT2B (pA2 = 7.5 in rat stomach fundus preparations). It is selective for 5-HT2C and 5-HT2B over 5-HT1A, 5-HT2A, 5-HT1D, 5-HT3, benzodiazepine, GABAA, alpha1-, alpha2A-, alpha2B-, beta1-, and...
| Keywords: | N-(1-methyl-1H-indol-5-yl)-N'-3-pyridinyl-urea, monohydrochloride |
| Application: | 5-HT2C / 5-HT2B dual antagonist |
| CAS | 143797-62-0 |
| MW: | 302.8 D |
From 49.00€
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SB-200646A
Item number: TGM-T22423-1mL
Description: SB-200646A is an orally active, selective antagonist of 5-HT2B/2C over 5-HT2A receptor with pKi of 7.5, 6.9 and 5.2 for 5-HT2B, 5-HT2C and 5-HT2A, respectively. SB-200646A exerts anxiolytic and electrophysiological properties in vivo. Target: 5-HT Receptor. Smiles: Cl.Cn1ccc2cc(NC(=O)Nc3cccnc3)ccc12....
| Application: | 5-HT2C / 5-HT2B dual antagonist |
| CAS | 143797-62-0 |
| MW: | 302.76 D |
From 34.00€
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