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Item number: Cay18128-5

Elacridar is a dual inhibitor of P-glycoprotein (MRP-1, ABCB1) and breast cancer resistance protein (BCRP, ABCG2). It maximally inhibits P-glycoprotein in isolated human peripheral blood leukocytes at 200 nM. Elacridar blocks the activity of P-glycoprotein at the blood-brain barrier, altering the pharmacokinetics of...

Keywords:	GF120918, GG918, GW0918,...
Application:	ABCB1 inhibitor, ABCG2 inhibitor
CAS	143664-11-3
MW:	563.6 D

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Elacridar

Item number: TGM-T2657-10mg

Description: Elacridar (GG918) (GF120918) is an effective BCRP and P-gp (MDR-1) inhibitor. Target: BCRP, P-gp. Smiles: COc1cc2CCN(CCc3ccc(NC(=O)c4cccc5c4[nH]c4c(OC)cccc4c5=O)cc3)Cc2cc1OC. References: Tang SC, et al. Int J Cancer. 2014, 134(6), 1484-1494.

Keywords:	GW0918, GF120918, GG918, GW120918
CAS	143664-11-3
MW:	563.64 D

From 34.00€ *

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