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FRAX1036
Item number: TGM-T6839-100mg
Description: FRAX-1036 is a effective and selective PAK1 inhibitor. Target: PAK. Smiles: CCn1c2nc(NCCC3CCN(C)CC3)ncc2cc(-c2ccc(cc2Cl)-c2cncc(C)n2)c1=O. References: Ong CC, et al. Breast Cancer Res. 2015, 17:59.
| Application: | Potent, selective PAK1 inhibitor |
| CAS | 1432908-05-8 |
| MW: | 518.05 D |
From 46.00€
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FRAX1036
Item number: Cay20711-1
FRAX1036 is a selective inhibitor of p21-activated kinase 1 (PAK1), a serine/threonine kinase downstream of Rac1 and Cdc42 that is involved in tumorigenesis. It can induce apoptosis in breast cancer cells and has been shown to potentiate the activity of the microtubule stabilizing agent, docetaxel (Cay-11637)....
| Keywords: | 6-[2-chloro-4-(6-methyl-2-pyrazinyl)phenyl]-8-ethyl-2-[[2-(1-methyl-4-piperidinyl)ethyl]amino]-pyrido[2,3-d]pyrimidin-7(8H... |
| Application: | Potent, selective PAK1 inhibitor |
| CAS | 1432908-05-8 |
| MW: | 518.1 D |
From 65.00€
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