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K02288
Item number: TGM-T1914-100mg
Description: K 02288 is a novel small molecule inhibitor of ALK1/2/3/6. Target: TGF-beta/Smad, ALK. Smiles: COc1cc(cc(OC)c1OC)-c1cc(cnc1N)-c1cccc(O)c1. References: Sanvitale CE, et al. PLoS One. 2013, 8(4), e62721.
| Keywords: | K 02288 |
| Application: | ALK1 / ALK2 inhibitor |
| CAS | 1431985-92-0 |
| MW: | 352.38 D |
From 34.00€
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K02288
Item number: Cay16678-1
Activation of bone morphogenetic protein (BMP) type I receptors, also known as activin receptor-like kinases (ALK1-7), leads to the assembly of SMAD complexes, which translocate to the nucleus to induce transcriptional activation important for normal development and tissue repair. K02288 is a 2-aminopyridine-based...
| Keywords: | 3-[6-amino-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]-phenol |
| Application: | ALK1 / ALK2 inhibitor |
| CAS | 1431985-92-0 |
| MW: | 352.4 D |
From 52.00€
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