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OTSSP167 hydrochloride
Item number: TGM-T21559-100mg
Description: OTSSP167 hydrochloride is a highly potent inhibitor of MELK(IC50 : 0.41 nM). Target: MELK. Smiles: Cl.CN(C)C[C@H]1CC[C@@H](CC1)Nc1c(cnc2ccc(nc12)-c1cc(Cl)c(O)c(Cl)c1)C(C)=O. References: Chung S, Suzuki H, Miyamoto T, et al. Development of an orally-administrative MELK-targeting inhibitor that suppresses...
| CAS | 1431698-10-0 |
| MW: | 523.88 D |
From 34.00€
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OTSSP167 (hydrochloride)
Item number: Cay16873-1
Maternal embryonic leucine zipper kinase (MELK) is a serine/threonine kinase that regulates signaling central to cell cycling, stem cell renewal, apoptosis, and other cellular processes. MELK is overexpressed in some forms of cancer, particularly those with aggressive undifferentiated tumors. OTSSP167 is a potent...
| Keywords: | 1-(6-(3,5-dichloro-4-hydroxyphenyl)-4-(((1r,4r)-4-((dimethylamino)methyl)cyclohexyl)amino)-1,5-naphthyridin-3-yl)ethan-1-o... |
| Application: | MELK inhibitor |
| CAS | 1431698-10-0 |
| MW: | 523.9 D |
From 85.00€
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OTSSP167 Hydrochloride
Item number: LKT-O783743.1
MELK inhibitor.
| Keywords: | OTS167 Hydrochloride, OTSSP167 (hydrochloride), OTSSP167 HCL |
| Application: | MELK inhibitor |
| CAS | 1431698-10-0 |
| MW: | 523.88 D |
From 123.00€
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