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Item number: Cay15066-1

HPOB is a potent inhibitor of histone deacetylase 6 (HDAC6, IC50 = 56 nM). It is at least 30-fold less effective against other HDACs. Through its effects on HDAC6, HPOB induces acetylation of alpha-tubulin but not histones. HPOB reduces the growth, but not the viability, of normal and transformed cells. It enhances...

Keywords:	4-[(hydroxyamino)carbonyl]-N-(2-hydroxyethyl)-N-phenyl-benzeneacetamide
Application:	HDAC6 inhibitor
CAS	1429651-50-2
MW:	314.3 D

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