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OXF BD 02
Item number: Cay14811-10
OXF BD 02 is an inhibitor of bromodomain 1 (BD1) in bromodomain-containing protein 4 (BRD4, IC50 = 382 nM). It is selective for BRD4 BD1 over a panel of 60 bromodomain-containing proteins but does inhibit CREB-binding protein (CBP) at 25 µM. OXF BD 02 is cytotoxic to MV4-11 acute myeloid leukemia (AML) cells (IC50 =...
| Keywords: | BRD4 Inhibitor Compound 8, 3-(3,5-dimethyl-4-isoxazolyl)-5-hydroxy-alpha-phenyl-benzenemethanol |
| Application: | BRD4 BD1 inhibitor |
| CAS | 1429129-68-9 |
| MW: | 295.3 D |
From 335.00€
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OXF BD 02
Item number: TGM-T23115-100mg
Description: OXF BD 02 is a potent and selective BRD4(1) inhibitor (IC50: 382 nM) with anticancer and anti-inflammatory activity. Target: Epigenetic Reader Domain. Smiles: CC=1C(C2=CC(C(O)C3=CC=CC=C3)=CC(O)=C2)=C(C)ON1. References: Hewings DS, et al. Optimization of 3,5-dimethylisoxazole derivatives as potent...
| Keywords: | OXFBD02 |
| CAS | 1429129-68-9 |
| MW: | 295.33 D |
From 95.00€
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