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Item number: Cay17339-1

U-73122 (Cay-70740) is an inhibitor of PLC-dependent processes, however, the mechanism of action remains unclear. The IC50 values for inhibition of platelet aggregation induced by collagen or thrombin are 0.6 and 5 µM, respectively. It also exhibits inhibitory activity against HIV-1 integrase with an IC50 value of 7...

Keywords:	1-[6-[[(17b)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-2,5-pyrrolidinedione
Application:	PLC inhibition negative control
CAS	142878-12-4
MW:	466.7 D

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U-73343

Item number: TGM-TQ0159-10mg

Description: U-73343 is an inactive analog of U-73122 and can be used as a negative control. It dose-dependently inhibits acid secretion irrespective of the stimulant. It is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor with an IC50 of 1-2.1 µM for PLC. Target: Phospholipase. Smiles:...

Keywords:	U 73343
CAS	142878-12-4
MW:	466.66 D

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