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Item number: Cay21895-1

JNJ-47965567 is a selective antagonist of the purinergic receptor P2X subtype 7 (P2X7), a ligand-gated ion channel. Activation of P2X receptors by BzATP (Cay-15577) induces calcium flux, which is reduced by JNJ-47965567 in 1321N1 cells transfected with recombinant P2X7 human, macaque, dog, rat, or mouse protein with...

Keywords:	2-(phenylthio)-N-[[tetrahydro-4-(4-phenyl-1-piperazinyl)-2H-pyran-4-yl]methyl]-3-pyridinecarboxamide
Application:	P2X7 antagonist
CAS	1428327-31-4
MW:	488.6 D

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JNJ-47965567

Item number: TGM-T4298-100mg

Description: JNJ-47965567 (JNJ-479655) is a selective antagonist of the purinergic receptor P2X subtype 7 (P2X7), a ligand-gated ion channel(with pKis of 7.9 and 8.7 for human and rat P2X7, respectively). Target: P2X Receptor. Smiles: O=C(NCC1(CCOCC1)N1CCN(CC1)c1ccccc1)c1cccnc1Sc1ccccc1. References: Pharmacological...

Keywords:	JNJ-479655
Application:	P2X7 antagonist
CAS	1428327-31-4
MW:	488.64 D

From 33.00€ *

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