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5-(N,N-hexamethylene)-Amiloride
5-(N,N-hexamethylene)-Amiloride

Item number: Cay29788-10

5-(N,N-hexamethylene)-Amiloride (HMA) is a derivative of amiloride (Cay-14409) with diverse biological activities. It is an allosteric antagonist of adenosine A2A receptors (Ki = 3.3 µM). HMA inhibits the cation-selective ion channel formed by the HIV-1 viral protein Vpu when used at a concentration of 50 µM, as...
Keywords: HMA, 3-amino-N-(aminoiminomethyl)-6-chloro-5-(hexahydro-1H-azepin-1-yl)-2-pyrazinecarboxamide
Application: Bioactive amiloride derivative, adenosine A2A receptor allosteric antagonist
CAS 1428-95-1
MW: 311.8 D
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