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A-484954
A-484954

Item number: Cay28279-1

A-484954 is an ATP-competitive inhibitor of eukaryotic elongation factor-2 kinase (eEF-2K, IC50 = 420 nM). It reduces eEF-2K autophosphorylation in PC3, HeLa, H460, H1299, and MDA-MB-231 cancer cells when used at a concentration of 75 µM.Formal Name:...
Keywords: 7-amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxo-pyrido[2,3-d]pyrimidine-6-carboxamide
Application: ATP-competitive eukaryotic elongation factor-2 kinase (eEF-2K) inhibitor
CAS 142557-61-7
MW: 289.3 D
From 49.00€ *
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A-484954
A-484954

Item number: TGM-TQ0137-100mg

Description: A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor. Target: CaMK, Parasite, Autophagy. Smiles: CCn1c(=O)n(C2CC2)c2nc(N)c(cc2c1=O)C(N)=O. References: Chen Z, et al. 1-Benzyl-3-cetyl-2-methylimidazolium iodide (NH125) induces phosphorylation of...
Keywords: A 484954
Application: ATP-competitive eukaryotic elongation factor-2 kinase (eEF-2K) inhibitor
CAS 142557-61-7
MW: 289.29 D
From 35.00€ *
Review