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Item number: Cay43468-10

An LSD1 inhibitor (IC50 = 13 nM), induces cell death in a panel of 12 ovarian cancer cell lines expressing mutant SWI/SNF (IC50s = 0.013-2.819 µM), increases secretion of IFN-gamma, IFN-beta, IL-1beta, IL-2, and IL-6 in COV434 cells, decreases the viability of primary NKT cells and T cells and reduces the...

Keywords:	Seclidemstat, 3-[(4-methyl-1-piperazinyl)sulfonyl]-benzoic acid, (2E)-2-[1-(5-chloro-2-hydroxyphenyl)ethylidene]hydrazide
Application:	LSD1 inhibitor
CAS	1423715-37-0
MW:	450.94 D

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Seclidemstat

Item number: TGM-T4527-100mg

Description: Seclidemstat (SP-2577) is an effective LSD1 inhibitor, with a mean IC50 of 127 nM. Target: Histone Demethylase. Smiles: CN1CCN(CC1)S(=O)(=O)c1cccc(c1)C(=O)N\N=C(/C)c1cc(Cl)ccc1O. References: SUBSTITUTED BENZOHYDRAZIDE ANALOGS AS HISTONE DEMETHYLAS EINHIBITOR S. WO/2017/004519 A1

Keywords:	SP-2577
Application:	Targets KDM1A (AOF2, LSD1)
CAS	1423715-37-0
MW:	450.94 D

From 39.00€ *

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