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SP2509
SP2509

Item number: Cay15487-10

Lysine-specific demethylase 1 (LSD1) is a protein lysine demethylase that specifically demethylates histone H3 lysine 4 (H3K4), resulting in transcriptional repression. SP2509 is a reversible inhibitor of LSD1 (IC50 = 13 nM). It has no effect on monoamine oxidases A and B. SP2509 attenuates the binding of LSD1 to...
Keywords: HCI-2509, LSD1 Inhibitor VII, 3-(4-morpholinylsulfonyl)-benzoic acid (2E)-2-[1-(5-chloro-2-hydroxyphenyl)ethylidene]hydrazide
Application: LSD1 inhibitor
CAS 1423715-09-6
MW: 437.9 D
From 32.00€ *
Review
SP2509
SP2509

Item number: SYN-1212-M001

Soluble in DMSO. LSD1 is a promising target for cancer therapy. Epigenetic control of histone methylation is frequently associated with oncogenesis and LSD1 is overexpressed in many types of cancer. siRNA knockdown of LSD1 has been shown to suppress growth of cancer cells. SP-2528 is a selective and reversible LSD1...
Keywords: SP-2509
Application: LSD1 inhibitor
CAS 1423715-09-6
MW: 437,9 D
From 158.00€ *
Review