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Item number: Cay43109-1

LY2922470 is an agonist of free fatty acid receptor 1 (FFAR1/GPR40). It induces calcium flux in HEK293 cells expressing FFAR1/GPR40 (EC50s = 7, 1, and 3 nM for the human, mouse, and rat receptor, respectively). LY2922470 (30 mg/kg) increases blood levels of glucagon-like peptide 1 (GLP-1) in fasted mice. It also...

Keywords:	(betaS)-4-[[5-[(3,4-dihydro-8-methoxy-1(2H)-quinolinyl)methyl]-2-thienyl]methoxy]-beta-1-propyn-1-yl-benzenepropanoic acid
Application:	FFAR1/GPR40 agonist
CAS	1423018-12-5
MW:	475.6 D

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LY2922470

Item number: TGM-T15810-100mg

Description: LY2922470 is a potent, selective G protein-coupled receptor 40 (GPR40) agonist, with EC50s of 7 nM for human GPR40, 1 nM for mouse GPR40 and 3 nM for rat GPR40, respectively. LY2922470 reduces glucose levels along and increases insulin and GLP-1 significantly. Target: GPR. Smiles:...

CAS	1423018-12-5
MW:	475.6 D

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