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Item number: Cay43557-1

ORG 274179-0 is a thyroid-stimulating hormone receptor (TSHR) allosteric antagonist. It inhibits TSHR activation induced by bovine TSH, human TSH, or the TSH-receptor-stimulating immunoglobulin M22 in reporter assays using CHO cells expressing the human receptor (IC50s = 30, 26, and 56 nM, respectively). ORG...

Keywords:	N-[(4S)-1-acetyl-1,2,3,4-tetrahydro-4-methyl-4-phenyl-6-quinolinyl]-3-(trifluoromethyl)-benzenepropanamide
Application:	Thyrotropin receptor (TSHR) allosteric antagonist
CAS	1421683-12-6
MW:	480.53 D

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