3 products were found matching "1421373-98-9"!
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AZ 5104
Item number: Cay17994-50
AZ 5104 is an inhibitor of mutant EGFRs (IC50 = 2 nM for EGFRL858R/T790M and EGFRT790M for both) and an active metabolite of AZD 9291 (Cay-16237). It is selective for these mutant EGFRs over wild-type EGFR (IC50 = 33 nM). AZ 5104 is formed from AZD 9291 by the cytochrome P450 (CYP) isoform CYP3A. It decreases...
| Keywords: | N-[2-[[2-(dimethylamino)ethyl]methylamino]-5-[[4-(1H-indol-3-yl)-2-pyrimidinyl]amino]-4-methoxyphenyl]-2-propenamide |
| Application: | EGFR inhibitor |
| CAS | 1421373-98-9 |
| MW: | 485.6 D |
From 85.00€
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AZ-5104
Item number: LKT-A980005.100
| Keywords: | AZ-5104, AZ 5104, AZ5104 |
| Application: | EGFR inhibitor |
| CAS | 1421373-98-9 |
| MW: | 485.59 D |
From 123.00€
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AZ-5104
Item number: TGM-T2491-5mg
Description: AZ5104 is a potent EGFR inhibitor. Target: EGFR. Smiles: COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1c[nH]c2ccccc12. References: Cross DA, et al. Cancer Discov. 2014, 4(9), 1046-1061.
| Application: | EGFR inhibitor |
| CAS | 1421373-98-9 |
| MW: | 485.58 D |
From 48.00€
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