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CYM 50769
Item number: Cay34484-1
CYM 50769 is a nonpeptide antagonist of neuropeptides B and W receptor 1 (NPBWR1). It inhibits neuropeptide W-induced activation of NPBWR1 (IC50 = 0.12 µM). CYM 50769 is selective for NPBWR1 over a panel of 30 G protein-coupled receptors (GPCRs), enzymes, transporters, and ion channels at 30 µM.Formal Name:...
| Keywords: | 5-chloro-2-(9H-fluoren-9-yl)-4-(4-methoxyphenoxy)-3(2H)-pyridazinone |
| Application: | NPBWR1 antagonist |
| CAS | 1421365-63-0 |
| MW: | 416.9 D |
From 52.00€
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CYM 50769
Item number: TGM-T22702-100mg
Description: CYM 50769 is a neuropeptide W/B receptor 1 (NPBWR1, GPR7) antagonist(IC50 = 0.12 µM). CYM 50769 inhibited NPW activation of NPBWR1 with a submicromolar IC50, and displayed high selectivity against a broad array of off-targets with pharmaceutical relevance. Target: Neuropeptide W. Smiles:...
| Application: | NPBWR1 antagonist |
| CAS | 1421365-63-0 |
| MW: | 416.86 D |
From 45.00€
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