2 products were found matching "1416799-28-4"!
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AMG 333
Item number: TGM-T5479-100mg
Description: AMG 333 is TRPM8 antagonist with an IC50 of 13 nM,a Clinical Candidate for the Treatment of Migraine. Target: TRP/TRPV Channel. Smiles: OC(=O)c1ccc(nc1)C(=O)N[C@@H](c1ccc(OC(F)(F)F)c(F)c1)c1ncccc1F. References: Horne DB, et al. Discovery of TRPM8 Antagonist (...
| Keywords: | AMG-333 |
| Application: | TRPM8 antagonist |
| CAS | 1416799-28-4 |
| MW: | 453.32 D |
From 31.00€
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AMG 333
Item number: Cay36825-10
AMG 333 is an antagonist of transient receptor potential melastatin 8 (TRPM8, IC50s = 13 and 20 for the human and rat channels, respectively). It is selective for TRPM8 over TRP vanilloid 1 (TRPV1), TRPV3, TRPV4, and TRP ankyrin 1 (TRPA1, IC50s = >20, >20, >20, and >40 µM, respectively), as well as a panel of 100...
| Keywords: | 6-[[[(S)-(3-fluoro-2-pyridinyl)[3-fluoro-4-(trifluoromethoxy)phenyl]methyl]amino]carbonyl]-3-pyridinecarboxylic acid |
| Application: | TRPM8 antagonist |
| CAS | 1416799-28-4 |
| MW: | 453.3 D |
From 43.00€
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