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Item number: Cay44337-10

Atuveciclib is an inhibitor of Cdk9/cyclin T1 (IC50 = 6 nM). It is selective for Cdk9/cyclin T1 over Cdk1/cyclin B, Cdk2/cyclin E, Cdk3/cyclin E, Cdk5/p35, Cdk6/cyclin D3, and Cdk7/cyclin H/Mat1 (IC50s = 1,100, 1,000, 890, 1,600, >10,000 and >10,000 nM, respectively). In vivo, atuveciclib (6. and 12. mg/kg) reduces...

Keywords:	BAY-1143572
Application:	Cdk9/cyclin T1 inhibitor
CAS	1414943-94-4
MW:	387.43 D

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