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Item number: Cay11999-10

Olopatadine is a histamine H1 receptor antagonist (Ki =41 nM). It is 1,059- and 4,177-fold selective for histamine H1 over H2 and H3 receptors, respectively. Olopatadine inhibits histamine-induced phosphoinositide turnover in isolated human conjunctival epithelial cells, isolated human corneal fibroblasts, and human...

Keywords:	ALO 4943A, KW 4679, 11Z-[3-(dimethylamino)propylidene]-6,11-dihydro-dibenz[b,e]oxepin-2-acetic acid, monohydrochloride
Application:	H1 histamine receptor antagonist
CAS	140462-76-6
MW:	373.9 D

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Olopatadine Hydrochloride

Item number: LKT-O4658.10

Olopatadine hydrochloride is an antihistamine clinically used to treat allergic rhinitis and allergic conjunctivitis. This compound acts as a mast cell stabilizer, preventing histamine and TNF- release from mast cells. Olopatadine is also an antagonist at histamine H1/2/3 receptors, although it is selective...

Application:	H1-receptor antagonist
CAS	140462-76-6
MW:	373.87 D

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