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ML277
ML277

Item number: TGM-T3303-100mg

Description: ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM). Target: Potassium Channel. Smiles: COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc(C)cc2)n1. References: Mattmann ME, Yu H, Lin Z, et al. Identification of...
Keywords: CID-53347902, ML-277
Application: KCNQ1 activator
CAS 1401242-74-7
MW: 471.59 D
From 34.00€ *
Review
ML-277
ML-277

Item number: Cay15193-5

Potassium (K+) channels are categorized by their mode of activation and the number of transmembrane segments. The voltage-gated six-transmembrane K+ channels include KCNQ1, first recognized for its role in cardiac function and subsequently in hearing, gastrointestinal chloride secretion, and other processes. ML-277...
Keywords: CID-53347902, (2R)-N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-[(4-methylphenyl)sulfonyl]-2-piperidinecarboxamide
Application: KCNQ1 activator
CAS 1401242-74-7
MW: 471.6 D
From 61.00€ *
Review