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Item number: TGM-T16483-1mg

Description: PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in research on cold-related pain. Target: TRP/TRPV Channel. Smiles: C[C@@H](N(Cc1cccc(c1)C(O)=O)C(=O)c1cnc2ccccc2c1)c1ccc(F)cc1. References: Andrews MD, et al. Discovery of a Selective TRPM8 Antagonist with Clinical...

Application:	TRPM8 antagonist
CAS	1398583-31-7
MW:	428.45 D

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PF-05105679

Item number: Cay29489-1

PF-05105679 is an antagonist of transient receptor potential melastatin 8 (TRPM8, IC50 = 103 nM for inhibition of voltage-activated currents in HEK293 cells expressing the human receptor). It is greater than 100-fold selective for TRPM8 over a panel of 90 receptors, ion channels, and enzymes. PF-05105679 inhibits...

Keywords:	3-[[[(1R)-1-(4-fluorophenyl)ethyl](3-quinolinylcarbonyl)amino]methyl]-benzoic acid
Application:	TRPM8 antagonist
CAS	1398583-31-7
MW:	428.5 D

From 44.00€ *

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