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Item number: Cay41838-1

DS-3032 is an inhibitor of the protein-protein interaction between murine double minute 2 (MDM2) and p53. It induces apoptosis in WaGa and PeTa Merkel cell carcinoma cells when used at a concentration of 100 nM. DS-3032 (1 µM) decreases the viability of p53 wild-type MKL-1 cells but not p53 knockout MLK-1 cells. In...

Keywords:	DS-3032b, Milademetan, RAIN-32,...
Application:	MDM2-p53 protein-protein interaction inhibitor
CAS	1398568-47-2
MW:	618.5 D

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Milademetan

Item number: TGM-T12040-100mg

Description: Milademetan (DS-3032) is an orally active and potent MDM2 inhibitor with antitumor activity that induces G1 cell cycle arrest, senescence, and apoptosis.Milademetan is used in the study of acute myeloid leukemia and solid tumors. Target: Mdm2, Others. Smiles:...

Keywords:	DS3032b, RAIN-32, DS-3032
Application:	Targets E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27] (MDM2)
CAS	1398568-47-2
MW:	618.53 D

From 31.00€ *

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