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Item number: TGM-T1992-100mg

Description: Mertansine (DM1) refers to the thiol-containing maytansinoid, DM1 (N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) attached to a monoclonal antibody through reaction of the thiol group with the SPP (N-succinimidyl 4-(2-pyridyldithio)) linker to create an antibody-drug conjugate or ADC. Experimental...

Keywords:	DM1, Maytansinoid DM1
CAS	139504-50-0
MW:	738.29 D

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Mertansine

Item number: Cay22483-25

Mertansine is a thiol-containing derivative of maytansine that is cytotoxic to human epidermoid carcinoma KB and human breast cancer SK-BR-3 cells (IC50 = 1.10 nM for both). Formulations containing mertansine have been studied for the treatment of multiple myeloma and squamous cell carcinoma.Formal Name:...

Keywords:	DM1 Compound, N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine
Application:	Maytansinoid tubulin inhibitor
CAS	139504-50-0
MW:	738.3 D

From 128.00€ *

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