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Narmafotinib
Item number: Cay45335-1
Narmafotinib is an inhibitor of focal adhesion kinase (FAK). It inhibits autophosphorylation of FAK at tyrosine 397 in MDA-MB-231 breast cancer cells (IC50 = 7 nM). Narmafotinib (80 mg/kg), in combination with bevacizumab, reduces tumor growth in an MDA-MB-231 orthotopic mouse model of breast cancer. It also induces...
| Keywords: | AMP945, CTx-0294945,... |
| Application: | FAK inhibitor |
| CAS | 1393653-34-3 |
| MW: | 527.59 D |
From 78.00€
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AMP-945
Item number: TGM-T9576-100mg
Description: AMP-945 is a proprietary focal adhesion kinase (FAK) inhibitor. Target: FAK. Smiles: COc1cc(ccc1Nc1ncc(c(CCc2ccccc2CC(N)=O)n1)C(F)(F)F)C1CCN(C)CC1. References: Amplia Therapeutics completes single-dose study of AMP945
| CAS | 1393653-34-3 |
| MW: | 527.58 D |
From 93.00€
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