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Glucagon Receptor Antagonist 4
Item number: Cay22164-1
Glucagon receptor antagonist 4 is an antagonist of the glucagon receptor (GCGR, Ki = 14 nM for the human recombinant receptor). It is greater than 230-fold selective for GCGR over the glucagon-like peptide 1 (GLP-1) receptor, as well as a panel of 69 receptors, ion channels, uptake sites, and enzymes at 10 µM....
| Keywords: | GCGR Antagonist IV, N-[4-[(1S)-1-[3,5-dimethyl-4-[4-(trifluoromethyl)-1H-pyrazol-1-yl]phenoxy]butyl]benzoyl]-beta-alanine |
| Application: | GCGR antagonist |
| CAS | 1393124-08-7 |
| MW: | 503.5 D |
From 51.00€
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PF-06291874
Item number: TGM-TQ0239-10mg
Description: PF-06291874 (Glucagon receptor antagonists-4) (Glucagon receptor antagonists-4) is a highly effective and orally active antagonist of the glucagon receptor. Target: Glucagon Receptor. Smiles: CCC[C@H](Oc1cc(C)c(c(C)c1)-n1cc(cn1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O. References: Guzman-Perez A et al. The...
| Keywords: | Glucagon receptor antagonists-4 |
| Application: | GCGR antagonist |
| CAS | 1393124-08-7 |
| MW: | 503.51 D |
From 52.00€
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