2 products were found matching "1392487-51-2"!

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Item number: Cay14397-1

G protein-coupled estrogen receptor (GPER), or GPR30, specifically binds natural and man-made estrogens. It is thought to be involved in estrogen-sensitive cancers. GPER knockout mice are fertile, although they exhibit thymic atrophy, impaired glucose tolerance, and altered bone growth. G-36 is a cell-permeable...

Keywords:	(4S)-rel-4-(6-bromo-1,3-benzodioxol-5-yl)-3aR,4,5,9bS-tetrahydro-8-(1-methylethyl)-3H-cyclopenta[c]quinoline
Application:	GPER antagonist
CAS	1392487-51-2
MW:	412.3 D

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G36

Item number: TGM-T22794-10mg

Description: G36 is a cell-permeable non-steroidal antagonist of GPER. G36 inhibits activation by either 17beta-estradiol or the GPER-selective agonist G-1 (IC50 = 112 and 165 nM, respectively). G36 has no detectable binding activity to either ERalpha or ERbeta. G36 blocks the activation of PI3K or calcium...

Keywords:	G-36
CAS	1392487-51-2
MW:	412.32 D

From 33.00€ *

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