3 products were found matching "1392136-43-4"!
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Verdinexor
Item number: TGM-T6123-100mg
Description: Verdinexor (KPT-335) (KPT-335), a specific XPO1/CRM1 inhibitor, are orally bioavailable. Target: CRM1. Smiles: FC(F)(F)c1cc(cc(c1)C(F)(F)F)-c1ncn(\C=C/C(=O)NNc2ccccn2)n1. References: London CA, et al. PLoS One. 2014, 9(2), e87585.
| Keywords: | KPT-335 |
| Application: | Targets exportin-1 (XPO1, CRM1) |
| CAS | 1392136-43-4 |
| MW: | 442.32 D |
From 31.00€
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Verdinexor
Item number: Cay26171-1
Verdinexor is a reversible inhibitor of Exportin I (XPO1/CRM1) with anticancer and antiviral activities. It inhibits the growth of OCI-Ly3, OCI-Ly10, and CLBL1 diffuse large B cell lymphoma (DLBCL) cells (IC50s = 2.1, 41.8, and 8.5 nM, respectively). Verdinexor inhibits XPO1/CRM1-mediated nuclear transport of...
| Keywords: | KPT-335, (2Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2-propenoic acid, 2-(2-pyridinyl)hydrazide |
| Application: | Nuclear export inhibitor, XPO1/CRM1 inhibitor |
| CAS | 1392136-43-4 |
| MW: | 442.3 D |
From 40.00€
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Verdinexor
Item number: LKT-V182685.1
CRM1/XPO1 inhibitor.
| Keywords: | KPT-335, 2-Propenoic acid, 3-(3-(3,5-bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-, 2-(2-pyridinyl)hydrazide, (2Z)-,... |
| Application: | Nuclear export inhibitor, XPO1/CRM1 inhibitor |
| CAS | 1392136-43-4 |
| MW: | 442.33 D |
From 95.00€
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