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Rilematovir
Item number: TGM-T15621-100mg
Description: Rilematovir (JNJ-678) is an inhibitor of fusion protein with antiviral activity and low cytotoxicity. Rilematovir can be used in studies about respiratory syncytial virus treatment. Target: RSV, EGFR. Smiles: CS(=O)(=O)CCCn1c(Cn2c3cnccc3n(CC(F)(F)F)c2=O)cc2cc(Cl)ccc12. References: Roymans D, et al....
| Keywords: | JNJ-678, JNJ-53718678 |
| CAS | 1383450-81-4 |
| MW: | 500.92 D |
From 42.00€
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COVID-19 Research
JNJ-53718678
Item number: Cay31720-10
JNJ-53718678 is an inhibitor of respiratory syncytial virus (RSV) fusion. JNJ-53718678 binds to and stabilizes the RSV fusion protein in its prefusion conformation. It reduces RSV replication in RSV-infected HeLa cells (IC50 = 0.5 nM) with a 50% cytotoxic concentration (CC50) of greater than 50 µM. JNJ-53718678...
| Keywords: | 3-[[5-chloro-1-[3-(methylsulfonyl)propyl]-1H-indol-2-yl]methyl]-1,3-dihydro-1-(2,2,2-trifluoroethyl)-2H-imidazo[4,5-c]pyri... |
| Application: | RSV (respiratory syncytial virus) fusion inhibitor |
| CAS | 1383450-81-4 |
| MW: | 500.9 D |
From 52.00€
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