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Item number: TGM-T21408-100mg

Description: DM1-SMe (DM1-SSMe) is a potent inhibitor of maytansinoid microtubular. DM1-SMe is about 3 to 10-fold more potent than the parent drug Maytansine, with IC50s of 0.003 to 0.01 nM for DM1-SMe in a panel of human tumor cell lines. Target: ADC Cytotoxin, Microtubule Associated. Smiles:...

Keywords:	DM1-SSMe
CAS	138148-68-2
MW:	784.38 D

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DM1-SMe

Item number: Cay22477-1

DM1-SMe is an analog of mertansine (DM1, Cay-22483) with a thiomethane cap attached to the sulfhydryl group. It has in vitro activity against the pediatric preclinical testing program (PPTP) panel of cancer cell lines with IC50 values of 0.002 to >3 nM.Formal Name:...

Keywords:	N2'-deacetyl-N2'-[3-(methyldithio)-1-oxopropyl]-maytansine
Application:	Maytansinoid microtubular inhibitor
CAS	138148-68-2
MW:	784.4 D

From 61.00€ *

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